CNOT3 Antibody

• Background:

  CNOT3 is a protein component of CCR4-NOT protein complex. Yeast CCR$-NOT is a global regulator of RNA polymerase II transcription. It is comprised of yeast NOT1 to NOT5, yeast CCR4 and additional proteins like yeast CAF1.

• NCBI Gene ID:

  4849

• Swiss Prot:

  O75175

• Accession Number:

  NP_055331

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CNOT3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CNOT3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  82 kDa

• Applications Notes:

  CNOT3 antibody can be used for detection of CNOT3 by ELISA at 1:312500. CNOT3 antibody can be used for detection of CNOT3 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CNOT3

• NCBI Official Name:

  CCR4-NOT transcription complex, subunit 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Aoki, T., et al., (2002) Biochem. Biophys. Res. Commun. 296 (5), 1097-1103.

• Other Product Names:

  CNOT3, NOT3, LENG2, NOT3H

• Tested Applications:

  ELISA, WB

• Protein ID:

  7657387

• Physical Properties:

  Liquid