CNOT7 Antibody

• Background :

  CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

• NCBI Gene ID :

  29883

• Swiss Prot :

  Q9UIV1

• Accession Number :

  NP_037486

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CNOT7.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CNOT7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  30 kDa, 28 kDa

• Applications Notes :

  CNOT7 antibody can be used for detection of CNOT7 by ELISA at 1:312500. CNOT7 antibody can be used for detection of CNOT7 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CNOT7

• NCBI Official Name :

  CCR4-NOT transcription complex, subunit 7

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kimura, K., (2006) Genome Res. 16 (1), 55-65.

• Other Product Names :

  CNOT7, CAF1, Caf1a, hCAF-1

• Tested Applications :

  ELISA, WB

• Protein ID :

  85067507

• Physical Properties :

  Liquid