CNOT8 Antibody

• Background:

  Ubiquitous transcription factor required for a diverse set of processes. The CCR4-NOT complex functions as general transcription regulation complex.

• NCBI Gene ID:

  9337

• Swiss Prot:

  Q9UFF9

• Accession Number:

  Q9UFF9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CNOT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 amino acids from the N-terminal region of human CNOT8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  34 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CNOT8

• NCBI Official Name:

  CCR4-NOT transcription complex subunit 8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ruan, L., et al. J. Biol. Chem. 285 (36) :27624-27631 (2010)

• Background Reference 02:

  Marchese, F.P., et al. J. Biol. Chem. 285 (36) :27590-27600 (2010)

• Background Reference 03:

  Piao, X., et al. Mol. Cell. Biol. 30 (6) :1486-1494 (2010)

• Background Reference 04:

  Lau, N.C., et al. Biochem. J. 422 (3) :443-453 (2009)

• Other Product Names:

  CCR4-NOT transcription complex subunit 8, CAF1-like protein, CALIFp, CAF2, CCR4-associated factor 8, Caf1b, CNOT8, CALIF, POP2

• Tested Applications:

  WB

• Protein ID:

  15213949

• Physical Properties:

  Liquid