HSF1 Antibody

• Background:

  The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene.

• NCBI Gene ID:

  3297

• Swiss Prot:

  Q00613

• Accession Number:

  Q00613

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the N-terminal region of human HSF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HSF1

• NCBI Official Name:

  Heat shock factor protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hayashida, N., et al. EMBO J. 29 (20) :3459-3469 (2010)

• Background Reference 02:

  Sangle, G.V., et al. Endocrinology 151 (9) :4455-4466 (2010)

• Background Reference 03:

  Shunmei, E., et al. Mol. Cells 29 (5) :527-531 (2010)

• Background Reference 04:

  Kim, S.A., et al. Int. J. Oncol. 36 (4) :867-872 (2010)

• Other Product Names:

  Heat shock factor protein 1, HSF 1, Heat shock transcription factor 1, HSTF 1, HSF1, HSTF1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  462333

• Physical Properties:

  Liquid