HSF1 (Ab 307) Antibody

• Background:

  DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

• NCBI Gene ID:

  3297

• Swiss Prot:

  Q00613

• Accession Number:

  NP_005517.1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  HSF1 (Ab-307) antibody was raised against a peptide sequence around aa. 305~309 (P-Q-S-P-R) derived from Human HSF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  82 kDa

• Specificity:

  This antibody detects endogenous level of total HSF1 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

• Symbol:

  HSF1

• NCBI Official Name:

  Heat shock transcription factor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guettouche T, et al. (2005) BMC Biochem ; 6 (1) : 4Wang X, et al. (2003) Mol Cell Biol ; 23 (17) : 6013-6026Jolly C, et al. (1999) Proc Natl Acad Sci USA; 96 (12) : 6769-6774.

• Other Product Names:

  HSTF1, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1, HSTF 1

• Tested Applications:

  WB, IHC

• Protein ID:

  5031767

• Physical Properties:

  Liquid