HSF4 Antibody

• Background:

  Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

• NCBI Gene ID:

  3299

• Swiss Prot:

  Q9ULV5-2

• Accession Number:

  NP_001529

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSF4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSF4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  50 kDa, 53 kDa

• Applications Notes:

  HSF4 antibody can be used for detection of HSF4 by ELISA at 1:312500. HSF4 antibody can be used for detection of HSF4 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  HSF4

• NCBI Official Name:

  Heat shock transcription factor 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65.

• Other Product Names:

  HSF4, CTM, CTRCT5

• Tested Applications:

  ELISA, WB

• Protein ID:

  100913211

• Physical Properties:

  Liquid