HCLS1 Antibody

• Background:

  Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

• NCBI Gene ID:

  3059

• Swiss Prot:

  P14317

• Accession Number:

  P14317

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HCLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-391 amino acids from the C-terminal region of human HCLS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HCLS1

• NCBI Official Name:

  Hematopoietic lineage cell-specific protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Muzio, M., et al. Leukemia 21 (9) :2067-2070 (2007)

• Background Reference 02:

  Lim, J., et al. Cell 125 (4) :801-814 (2006)

• Background Reference 03:

  Hao, J.J., et al. J. Biol. Chem. 280 (45) :37988-37994 (2005)

• Background Reference 04:

  Tao, W.A., et al. Nat. Methods 2 (8) :591-598 (2005)

• Other Product Names:

  Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  317373440

• Physical Properties:

  Liquid