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USO1 Antibody

CAT: 0223-57-431Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-431Size:400 µL
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Background
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
NCBI Gene ID
8615
Swiss Prot
O60763
Accession Number
O60763
Host
Rabbit
Reactivity
Human
Immunogen
This USO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 932-960 amino acids from the C-terminal region of human USO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Symbol
USO1
NCBI Official Name
General vesicular transport factor p115
NCBI Organism
Homo sapiens
Background Reference 01
Striegl, H., et al. PLoS ONE (2), E8991 (2010) :
Background Reference 02
Merk, M., et al. J. Immunol. 182 (11) :6896-6906 (2009)
Background Reference 03
Mukherjee, S., et al. J. Biol. Chem. 284 (3) :1709-1717 (2009)
Background Reference 04
Striegl, H., et al. PLoS ONE (2), E4656 (2009) :
Other Product Names
General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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