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CYB5A Antibody

CAT: 0223-57-429Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-429Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
1528
Swiss Prot
P00167
Accession Number
P00167
Host
Rabbit
Reactivity
Human
Immunogen
This CYB5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CYB5A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Symbol
CYB5A
NCBI Official Name
Cytochrome b5
NCBI Organism
Homo sapiens
Background Reference 01
Gardner, A.M., et al. J. Biol. Chem. 285 (31) :23850-23857 (2010)
Background Reference 02
Kok, R.C., et al. J. Clin. Endocrinol. Metab. 95 (3) :994-999 (2010)
Background Reference 03
Sacco, J.C., et al. Pharmacogenet. Genomics 20 (1) :26-37 (2010)
Background Reference 04
Maghzal, G.J., et al. J. Biol. Chem. 283 (18) :12014-12025 (2008)
Other Product Names
Cytochrome b5, Microsomal cytochrome b5 type A, MCB5, CYB5A, CYB5
Tested Applications
WB, IHC-P
Protein ID
117809
Physical Properties
Liquid

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