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CYBA Antibody

CAT: 0223-56-245Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-245Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta) . This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
NCBI Gene ID
1535
Swiss Prot
P13498
Accession Number
P13498
Host
Rabbit
Reactivity
Human
Immunogen
This CYBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human CYBA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Symbol
CYBA
NCBI Official Name
Cytochrome b-245 light chain
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Katakami, N., et al. Atherosclerosis 212 (2) :534-538 (2010)
Background Reference 03
Tu, Y.C., et al. Acta Pharmacol. Sin. 31 (7) :874-880 (2010)
Background Reference 04
Moreno, M.U., et al. Drug News Perspect. 23 (5) :316-324 (2010)
Other Product Names
Cytochrome b-245 light chain, Cytochrome b (558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox, CYBA
Tested Applications
WB, IF
Protein ID
311033459
Physical Properties
Liquid

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