NPPC Antibody

• Background:

  Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.

• NCBI Gene ID:

  4880

• Swiss Prot:

  P23582

• Accession Number:

  P23582

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NPPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the C-terminal region of human NPPC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  13 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NPPC

• NCBI Official Name:

  C-type natriuretic peptide

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lippert, S.K., et al. J. Immunol. Methods 362 (1-2), 32-37 (2010) :

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03:

  Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)

• Background Reference 04:

  Wang, Y., et al. J. Cardiovasc. Pharmacol. 55 (1) :62-66 (2010)

• Other Product Names:

  C-type natriuretic peptide, CNP-22, CNP-29, CNP-53, NPPC, CNP2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  113850

• Physical Properties:

  Liquid