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NPPC polyclonal antibody

CAT: 0384-BS60381-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60381-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) . ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control . ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage . The genes which encode for ANP and BNP map to human chromosome 1p36.2 . The gene which encodes for CNP maps to human chromosome 2q24-qter .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
C-type natriuretic peptide; Cleaved into the following 3 chains:CNP-22; CNP-29; CNP-53; NPPC; CNP2
Swiss Prot
P23582
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human NPPC.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 7 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NPPC polyclonal antibody detects endogenous levels of NPPC protein.
Applications Notes
Western blot (WB) analysis of NPPC polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat heart tissue lysate
Host or Source
Rabbit

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