CELA2A Antibody

• Background:

  Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.

• NCBI Gene ID:

  63036

• Swiss Prot:

  P08217

• Accession Number:

  P08217

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human CELA2A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CELA2A

• NCBI Official Name:

  Chymotrypsin-like elastase family member 2A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 03:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 04:

  Lausen, J., et al. Oncogene 25 (9) :1349-1357 (2006)

• Other Product Names:

  Chymotrypsin-like elastase family member 2A, Elastase-2A, CELA2A, ELA2A

• Tested Applications:

  WB

• Protein ID:

  119255

• Physical Properties:

  Liquid