COPB1 Antibody

• Background:

  This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described.

• NCBI Gene ID:

  1315

• Swiss Prot:

  P53618

• Accession Number:

  P53618

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the Central region of human COPB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  107 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  COPB1

• NCBI Official Name:

  Coatomer subunit beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Burman, J.L., et al. J. Biol. Chem. 283 (33) :22774-22786 (2008)

• Background Reference 02:

  Lippincott-Schwartz, J., et al. Trends Cell Biol. 16 (10), E1-E4 (2006) :

• Background Reference 03:

  Huang, L., et al. Mol. Biol. Rep. 29 (3) :317-323 (2002)

• Background Reference 04:

  Paulsson, K.M., et al. J. Biol. Chem. 277 (21) :18266-18271 (2002)

• Other Product Names:

  Coatomer subunit beta, Beta-coat protein, Beta-COP, COPB1, COPB

• Tested Applications:

  WB

• Protein ID:

  116241311

• Physical Properties:

  Liquid