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PTF1A Antibody

CAT: 0223-57-324Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-324Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
NCBI Gene ID
256297
Swiss Prot
Q7RTS3
Accession Number
Q7RTS3
Host
Rabbit
Reactivity
Human
Immunogen
This PTF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the C-terminal region of human PTF1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PTF1A
NCBI Official Name
Pancreas transcription factor 1 subunit alpha
NCBI Organism
Homo sapiens
Background Reference 01
Meredith, D.M., et al. J. Neurosci. 29 (36) :11139-11148 (2009)
Background Reference 02
Rodolosse, A., et al. Biochem. J. 418 (2) :463-473 (2009)
Background Reference 03
Tutak, E., et al. Genet. Couns. 20 (2) :147-152 (2009)
Background Reference 04
Yamada, M., et al. J. Neurosci. 27 (41) :10924-10934 (2007)
Other Product Names
Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48, PTF1A, BHLHA29, PTF1P48
Tested Applications
WB
Protein ID
74749931
Physical Properties
Liquid

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