NONO Antibody

CAT: 0223-57-268Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-268Size:400 µL
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Background
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq].
NCBI Gene ID
4841
Swiss Prot
Q15233
Accession Number
Q15233
Host
Rabbit
Reactivity
Human
Immunogen
This NONO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human NONO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
NONO
NCBI Official Name
Non-POU domain-containing octamer-binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Marko, M., et al. Exp. Cell Res. 316 (3) :390-400 (2010)
Background Reference 02
Dong, X., et al. Mol. Endocrinol. 23 (8) :1147-1160 (2009)
Background Reference 03
Sikora, D., et al. Virology 390 (1) :71-78 (2009)
Background Reference 04
Clemson, C.M., et al. Mol. Cell 33 (6) :717-726 (2009)
Other Product Names
Non-POU domain-containing octamer-binding protein, NonO protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, NMT55, p54 (nrb), p54nrb, NONO, NRB54
Tested Applications
WB, IHC-P
Protein ID
67469924
Physical Properties
Liquid

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