NONO Antibody

• Background :

  This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq].

• NCBI Gene ID :

  4841

• Swiss Prot :

  Q15233

• Accession Number :

  Q15233

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This NONO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human NONO.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  54 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  NONO

• NCBI Official Name :

  Non-POU domain-containing octamer-binding protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Marko, M., et al. Exp. Cell Res. 316 (3) :390-400 (2010)

• Background Reference 02 :

  Dong, X., et al. Mol. Endocrinol. 23 (8) :1147-1160 (2009)

• Background Reference 03 :

  Sikora, D., et al. Virology 390 (1) :71-78 (2009)

• Background Reference 04 :

  Clemson, C.M., et al. Mol. Cell 33 (6) :717-726 (2009)

• Other Product Names :

  Non-POU domain-containing octamer-binding protein, NonO protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, NMT55, p54 (nrb), p54nrb, NONO, NRB54

• Tested Applications :

  WB, IHC-P

• Protein ID :

  67469924

• Physical Properties :

  Liquid