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NR0B1 Antibody

CAT: 0223-57-262Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-262Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
NCBI Gene ID
190
Swiss Prot
P51843
Accession Number
P51843
Host
Rabbit
Reactivity
Human
Immunogen
This NR0B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human NR0B1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
NR0B1
NCBI Official Name
Nuclear receptor subfamily 0 group B member 1
NCBI Organism
Homo sapiens
Background Reference 01
Li, N., et al. J. Clin. Endocrinol. Metab. 95 (9), E104-E111 (2010) :
Background Reference 02
Nedumaran, B., et al. J. Biol. Chem. 285 (12) :9221-9232 (2010)
Background Reference 03
Kinsey, M., et al. Cancer Res. 69 (23) :9047-9055 (2009)
Background Reference 04
Nagl, F., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1146-C1156 (2009) :
Other Product Names
Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, NR0B1, AHC, DAX1
Tested Applications
WB, IHC-P
Protein ID
20532385
Physical Properties
Liquid

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