PPP3CA Antibody

• Background:

  Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.

• NCBI Gene ID:

  5530

• Swiss Prot:

  Q08209

• Accession Number:

  Q08209

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPP3CA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-466 amino acids from the C-terminal region of human PPP3CA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPP3CA

• NCBI Official Name:

  Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  He, Z.H., et al. Eur. J. Appl. Physiol. 110 (4) :761-767 (2010)

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03:

  Chiocco, M.J., et al. Subst Use Misuse 45 (11) :1809-1826 (2010)

• Background Reference 04:

  Yang, D., et al. Int. J. Mol. Med. 26 (1) :159-164 (2010)

• Other Product Names:

  Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CNA

• Tested Applications:

  WB

• Protein ID:

  1352673

• Physical Properties:

  Liquid