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PPP2CA Antibody

CAT: 0223-60-912Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-912Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
NCBI Gene ID
5515
Swiss Prot
P67775
Accession Number
P67775
Host
Rabbit
Reactivity
Mouse
Immunogen
This PPP2CA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human PPP2CA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Pig, Rabbit, Rat, Drosophila
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP2CA
NCBI Official Name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Jayadeva, G., et al. J. Biol. Chem. 285 (39) :29863-29873 (2010)
Background Reference 03
Pradhan, S., et al. J. Biol. Chem. 285 (38) :29059-29068 (2010)
Background Reference 04
Schmitz, M.H., et al. Nat. Cell Biol. 12 (9) :886-893 (2010)
Other Product Names
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA
Tested Applications
WB
Protein ID
54038809
Physical Properties
Liquid

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