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STAT4 Antibody

CAT: 0223-57-222Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-222Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
NCBI Gene ID
6775
Swiss Prot
Q14765
Accession Number
Q14765
Host
Rabbit
Reactivity
Human
Immunogen
This STAT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human STAT4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Symbol
STAT4
NCBI Official Name
Signal transducer and activator of transcription 4
NCBI Organism
Homo sapiens
Background Reference 01
Plant, D., et al. Ann. Rheum. Dis. 69 (8) :1548-1553 (2010)
Background Reference 02
Gestermann, N., et al. Genes Immun. 11 (5) :432-438 (2010)
Background Reference 03
Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)
Background Reference 04
Vuong, M.T., et al. PLoS ONE (5), E10559 (2010) :
Other Product Names
Signal transducer and activator of transcription 4, STAT4
Tested Applications
WB, IHC-P, IF
Protein ID
6226158
Physical Properties
Liquid

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