MID2 Antibody

• Background:

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

• NCBI Gene ID:

  11043

• Swiss Prot:

  Q9UJV3

• Accession Number:

  Q9UJV3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human MID2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  83 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MID2

• NCBI Official Name:

  Probable E3 ubiquitin-protein ligase MID2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lim, J., et al. Cell 125 (4) :801-814 (2006)

• Background Reference 02:

  Jehee, F.S., et al. Am. J. Med. Genet.139 (3) :221-226 (2005)

• Background Reference 03:

  Yap, M.W., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (29) :10786-10791 (2004)

• Background Reference 04:

  Short, K.M., et al. BMC Cell Biol. 3, (2002) :

• Other Product Names:

  Probable E3 ubiquitin-protein ligase MID2, 632-, Midin-2, Midline defect 2, Midline-2, RING finger protein 60, Tripartite motif-containing protein 1, MID2, FXY2, RNF60, TRIM1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  294862489

• Physical Properties:

  Liquid