RegisterLogin

MID1 Antibody

CAT: 0223-28-162Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-162Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing; however, the full length nature of two variants has not been determined.
NCBI Gene ID
4281
Swiss Prot
O15344
Accession Number
NP_000372
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MID1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MID1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
75 kDa, 75 kDa, 62 kDa
Applications Notes
MID1 antibody can be used for detection of MID1 by ELISA at 1:312500. MID1 antibody can be used for detection of MID1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MID1
NCBI Official Name
Midline 1 (Opitz/BBB syndrome)
NCBI Organism
Homo sapiens
Background Reference 01
Winter, J., et al., (2004) Hum. Genet. 114 (6), 541-552.
Other Product Names
MID1, OS, FXY, OSX, OGS1, XPRF, BBBG1, GBBB1, MIDIN, RNF59, ZNFXY, TRIM18
Tested Applications
ELISA, WB
Protein ID
4557753
Physical Properties
Liquid

Related Products

CatalogName
45-887MID2 Antibody
57-170MID2 Antibody
45-887PMID2 Peptide
64-160WAS Antibody
13-349WAS Antibody
60-596WAS Antibody
63-408DGKB Antibody
63-412AK5 Antibody
63-420HK3 Antibody
63-422HK2 Antibody

Alternative Products

CatalogName
MBS7132739-01MID1 Antibody
MBS2539548-01MID1 Polyclonal Antibody
MBS9241080-01Anti-MID1 Antibody
MBS8561562-01MID1

Popular Products