APCDD1 Antibody

• Background:

  This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.

• NCBI Gene ID:

  147495

• Swiss Prot:

  Q8J025

• Accession Number:

  Q8J025

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This APCDD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human APCDD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  APCDD1

• NCBI Official Name:

  Protein APCDD1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shimomura, Y., et al. Nature 464 (7291) :1043-1047 (2010)

• Background Reference 02:

  Takahashi, M., et al. Cancer Res. 62 (20) :5651-5656 (2002)

• Other Product Names:

  HGNC:15718

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74728445

• Physical Properties:

  Liquid