SGPP1 Antibody

• Background:

  Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]) .[supplied by OMIM].

• NCBI Gene ID:

  81537

• Swiss Prot:

  Q9BX95

• Accession Number:

  Q9BX95

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SGPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SGPP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  49 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SGPP1

• NCBI Official Name:

  Sphingosine-1-phosphate phosphatase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hicks, A.A., et al. PLoS Genet. (10), E1000672 (2009) :

• Background Reference 02:

  Le Stunff, H., et al. J. Biol. Chem. 282 (47) :34372-34380 (2007)

• Background Reference 03:

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Background Reference 04:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  Sphingosine-1-phosphate phosphatase 1, SPPase1, Spp1, hSPP1, hSPPase1, 313-, Sphingosine-1-phosphatase 1, SGPP1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  46577706

• Physical Properties:

  Liquid