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SGPL1 Antibody

CAT: 0223-56-615Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-615Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SGPL1 cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.
NCBI Gene ID
8879
Swiss Prot
O95470
Accession Number
O95470
Host
Rabbit
Reactivity
Human
Immunogen
This SGPL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human SGPL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
64 kDa
Fragment
Rabbit Ig
Symbol
SGPL1
NCBI Official Name
Sphingosine-1-phosphate lyase 1
NCBI Organism
Homo sapiens
Background Reference 01
Seo, Y.J., et al. J. Virol. 84 (16) :8124-8131 (2010)
Background Reference 02
Vogel, P., et al. PLoS ONE (1), E4112 (2009) :
Background Reference 03
Peest, U., et al. J. Cell. Biochem. 104 (3) :756-772 (2008)
Background Reference 04
Morgan, A.R., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 144B (6), 762-770 (2007) :
Other Product Names
Sphingosine-1-phosphate lyase 1, S1PL, SP-lyase 1, SPL 1, hSPL, Sphingosine-1-phosphate aldolase, SGPL1, KIAA1252
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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