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FGD2 Antibody

CAT: 0223-56-911Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-911Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FGD2 activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate (By similarity) .
NCBI Gene ID
221472
Swiss Prot
Q7Z6J4
Accession Number
Q7Z6J4
Host
Rabbit
Reactivity
Mouse
Immunogen
This FGD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human FGD2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Symbol
FGD2
NCBI Official Name
FYVE, RhoGEF and PH domain-containing protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Huber, C., et al. J. Biol. Chem. 283 (49) :34002-34012 (2008)
Background Reference 02
Delague, V., et al. Am. J. Hum. Genet. 81 (1) :1-16 (2007)
Background Reference 03
Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)
Background Reference 04
Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
Other Product Names
FYVE, RhoGEF and PH domain-containing protein 2, Zinc finger FYVE domain-containing protein 4, FGD2, ZFYVE4
Tested Applications
WB, IHC-P
Protein ID
61213572
Physical Properties
Liquid

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