FGD6 Antibody

• Background:

  Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

• NCBI Gene ID:

  55785

• Swiss Prot:

  Q6ZV73

• Accession Number:

  Q6ZV73

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FGD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1324-1352 amino acids from the C-terminal region of human FGD6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  161 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  FGD6

• NCBI Official Name:

  FYVE, RhoGEF and PH domain-containing protein 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Barrios-Rodiles, M., et al. Science 307 (5715) :1621-1625 (2005)

• Background Reference 02:

  Jin, J., et al. Curr. Biol. 14 (16) :1436-1450 (2004)

• Other Product Names:

  FYVE, RhoGEF and PH domain-containing protein 6, Zinc finger FYVE domain-containing protein 24, FGD6, KIAA1362, ZFYVE24

• Tested Applications:

  WB, IHC-P

• Protein ID:

  61213484

• Physical Properties:

  Liquid