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ORC5L Antibody

CAT: 0223-56-853Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-853Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
NCBI Gene ID
5001
Swiss Prot
O43913
Accession Number
O43913
Host
Rabbit
Reactivity
Mouse
Immunogen
This ORC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human ORC5L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ORC5
NCBI Official Name
Origin recognition complex subunit 5
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)
Background Reference 03
Siddiqui, K., et al. J. Biol. Chem. 282 (44) :32370-32383 (2007)
Background Reference 04
Clarke, C.A., et al. Biochem. J. 388 (PT 2), 705-712 (2005) :
Other Product Names
Origin recognition complex subunit 5, ORC5, ORC5L
Tested Applications
WB
Physical Properties
Liquid

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