Products for Research Use Only

HMFG Antibody

CAT: 0223-56-718Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-718Size:400 µL
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Background
HMFG plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity) . Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid.
NCBI Gene ID
4240
Swiss Prot
Q08431
Accession Number
Q08431
Host
Rabbit
Reactivity
Human
Immunogen
This HMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human HMFG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
MFGE8
NCBI Official Name
Lactadherin
NCBI Organism
Homo sapiens
Background Reference 01
Yamaguchi, H., et al. Eur. J. Immunol. 40 (6) :1778-1785 (2010)
Background Reference 02
Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :
Background Reference 03
Hu, C.Y., et al. Lupus 18 (8) :676-681 (2009)
Background Reference 04
Fu, Z., et al. Circ. Res. 104 (12) :1337-1346 (2009)
Other Product Names
Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8
Tested Applications
WB, Flow
Protein ID
2506380
Physical Properties
Liquid

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