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POFUT2 Antibody

CAT: 0223-56-696Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-696Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) -like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]) .
NCBI Gene ID
23275
Swiss Prot
Q9Y2G5
Accession Number
Q9Y2G5
Host
Rabbit
Reactivity
Human
Immunogen
This POFUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human POFUT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Symbol
POFUT2
NCBI Official Name
GDP-fucose protein O-fucosyltransferase 2
NCBI Organism
Homo sapiens
Background Reference 01
Feng, T., et al. Hum. Genet. 128 (3) :269-280 (2010)
Background Reference 02
Luo, Y., et al. J. Biol. Chem. 281 (14) :9385-9392 (2006)
Background Reference 03
Luo, Y., et al. J. Biol. Chem. 281 (14) :9393-9399 (2006)
Background Reference 04
Menzel, O., et al. Genomics 84 (2) :320-330 (2004)
Other Product Names
GDP-fucose protein O-fucosyltransferase 2, Peptide-O-fucosyltransferase 2, O-FucT-2, POFUT2, C21orf80, FUT13, KIAA0958
Tested Applications
WB, IHC-P
Protein ID
59803123
Physical Properties
Liquid

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