DSN1 Antibody

• Background:

  This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  79980

• Swiss Prot:

  Q9H410

• Accession Number:

  Q9H410

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the C-terminal region of human DSN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  40 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DSN1

• NCBI Official Name:

  Kinetochore-associated protein DSN1 homolog

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yang, Y., et al. J. Biol. Chem. 283 (39) :26726-26736 (2008)

• Background Reference 02:

  Cheeseman, I.M., et al. Nat. Rev. Mol. Cell Biol. 9 (1) :33-46 (2008)

• Background Reference 03:

  Kiyomitsu, T., et al. Dev. Cell 13 (5) :663-676 (2007)

• Background Reference 04:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names:

  Kinetochore-associated protein DSN1 homolog, DSN1, C20orf172, MIS13

• Tested Applications:

  WB

• Protein ID:

  28201793

• Physical Properties:

  Liquid