RFX2 Antibody

• Background:

  This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.

• NCBI Gene ID:

  5990

• Swiss Prot:

  P48378

• Accession Number:

  P48378

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RFX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human RFX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  80 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RFX2

• NCBI Official Name:

  DNA-binding protein RFX2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Purvis, T.L., et al. Gene 460 (1-2), 20-29 (2010) :

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care (2010) In press :

• Background Reference 03:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 04:

  Horvath, G.C., et al. Biol. Reprod. 71 (5) :1551-1559 (2004)

• Other Product Names:

  DNA-binding protein RFX2, Regulatory factor X 2, RFX2

• Tested Applications:

  WB

• Protein ID:

  254763325

• Physical Properties:

  Liquid