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SYK Antibody

CAT: 0223-56-631Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-631Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
NCBI Gene ID
6850
Swiss Prot
P43405
Accession Number
P43405
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-305 amino acids from human SYK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SYK
NCBI Official Name
Tyrosine-protein kinase SYK
NCBI Organism
Homo sapiens
Background Reference 01
Thomas, D.H., et al. Blood 116 (14) :2570-2578 (2010)
Background Reference 02
Poeck, H., et al. J. Mol. Med. 88 (8) :745-752 (2010)
Background Reference 03
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 04
Pechloff, K., et al. J. Exp. Med. 207 (5) :1031-1044 (2010)
Other Product Names
Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK
Tested Applications
WB
Protein ID
1174527
Physical Properties
Liquid

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