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NPHP3 Antibody

CAT: 0223-56-625Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-625Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin and may function in renal tubular development and function. Mutations in this gene are associated with nephronophthisis type 3. Multiple splice variants have been described but their full-length nature has not been determined.
NCBI Gene ID
27031
Swiss Prot
Q7Z494
Accession Number
Q7Z494
Host
Rabbit
Reactivity
Human
Immunogen
This NPHP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human NPHP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
151 kDa
Fragment
Rabbit Ig
Symbol
NPHP3
NCBI Official Name
Nephrocystin-3
NCBI Organism
Homo sapiens
Background Reference 01
Simpson, M.A., et al. Am. J. Kidney Dis. 53 (5) :790-795 (2009)
Background Reference 02
Tory, K., et al. Kidney Int. 75 (8) :839-847 (2009)
Background Reference 03
Bergmann, C., et al. Am. J. Hum. Genet. 82 (4) :959-970 (2008)
Background Reference 04
Hoefele, J., et al. J. Am. Soc. Nephrol. 18 (10) :2789-2795 (2007)
Other Product Names
Nephrocystin-3, NPHP3, KIAA2000
Tested Applications
WB, IHC-P
Protein ID
68565783
Physical Properties
Liquid

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