NPHP4 Antibody

• Background :

  This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  261734

• Swiss Prot :

  O75161

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1247-1426 of human NPHP4 (NP_055917.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  293T

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 157kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  NPHP4

• Positive Control 2 :

  A-549

• NCBI Official Name :

  Nephrocystin 4

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  POC1SLSN4, nephrocystin-4, POC10 centriolar protein homolog, nephroretinin

• Tested Applications :

  WB

• Physical Properties :

  Liquid