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STAMBP Antibody

CAT: 0223-56-589Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-589Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
NCBI Gene ID
10617
Swiss Prot
O95630
Accession Number
O95630
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This STAMBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human STAMBP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
STAMBP
NCBI Official Name
STAM-binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Sierra, M.I., et al. J. Biol. Chem. 285 (18) :13990-14004 (2010)
Background Reference 02
Hasdemir, B., et al. J. Biol. Chem. 284 (41) :28453-28466 (2009)
Background Reference 03
Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)
Background Reference 04
Wang, P., et al. BMC Genomics 10, 518 (2009) :
Other Product Names
STAM-binding protein, 3419-, Associated molecule with the SH3 domain of STAM, Endosome-associated ubiquitin isopeptidase, STAMBP, AMSH
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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