STAM Antibody

• Background:

  This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

• NCBI Gene ID:

  8027

• Swiss Prot:

  Q92783

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human STAM (NP_003464.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Symbol:

  STAM

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HeLa

• Positive Control 4:

  HepG2

• Positive Control 5:

  Mouse pancreas

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  Signal transducing adapter molecule 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Signal transducing adapter molecule 1, STAM-1, STAM, STAM1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid