STAB2 Antibody

• Background:

  This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF) -like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

• NCBI Gene ID:

  55576

• Swiss Prot:

  Q8WWQ8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1550-1850 of human STAB2 (NP_060034.9) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 277kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  STAB2

• Positive Control 2:

  BT-474

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Mouse eye

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  Stabilin 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FEEL2, FELE-2, FELL2, FEX2, HARE, SCARH1, stabilin-2, CD44-like precursor FELL, FAS1 EGF-like and X-link domain containing adhesion molecule-2, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2, hepatic hyaluronan clearance receptor, hyaluronan receptor for endocytosis, hyaluronic acid receptor for endocytosis

• Tested Applications:

  WB

• Physical Properties:

  Liquid