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STAM2 Antibody

CAT: 0223-57-437Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-437Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
NCBI Gene ID
10254
Swiss Prot
O75886
Accession Number
O75886
Host
Rabbit
Reactivity
Human
Immunogen
This STAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human STAM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
STAM2
NCBI Official Name
Signal transducing adapter molecule 2
NCBI Organism
Homo sapiens
Background Reference 01
Stuible, M., et al. J. Biol. Chem. 285 (31) :23899-23907 (2010)
Background Reference 02
Rismanchi, N., et al. Traffic 10 (2) :201-217 (2009)
Background Reference 03
Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)
Background Reference 04
Kong, C., et al. J. Biol. Chem. 282 (20) :15294-15301 (2007)
Other Product Names
Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein, STAM2, HBP
Tested Applications
WB
Physical Properties
Liquid

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