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ASS1 Antibody

CAT: 0223-56-532Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-532Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
445
Swiss Prot
P00966
Accession Number
P00966
Host
Rabbit
Reactivity
Human
Immunogen
This ASS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human ASS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
ASS1
NCBI Official Name
Argininosuccinate synthase
NCBI Organism
Homo sapiens
Background Reference 01
Hozyasz, K.K., et al. Arch. Oral Biol. 55 (11) :861-866 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Kobayashi, E., et al. Mol. Cancer Ther. 9 (3) :535-544 (2010)
Background Reference 04
Tsai, W.B., et al. Mol. Cancer Ther. 8 (12) :3223-3233 (2009)
Other Product Names
Argininosuccinate synthase, Citrulline--aspartate ligase, ASS1, ASS
Tested Applications
WB, IHC-P, Flow
Protein ID
20141195
Physical Properties
Liquid

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