ASS Antibody

• Background:

  ASS catalyzes the penultimate step of the arginine biosynthetic pathway.The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

• NCBI Gene ID:

  445

• Swiss Prot:

  P00966

• Accession Number:

  NP_446464

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ASS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  45 kDa, 47 kDa

• Applications Notes:

  ASS antibody can be used for detection of ASS by ELISA at 1:312500. ASS antibody can be used for detection of ASS by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ASS1

• NCBI Official Name:

  Argininosuccinate synthase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hao, G., (2004) J. Biol. Chem. 279 (35), 36192-36200.

• Other Product Names:

  ASS, ASS1, CTLN1, DKFZp434P0216, ASS

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  16950633

• Physical Properties:

  Liquid