GDF15 Antibody

• Background :

  Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

• NCBI Gene ID :

  9518

• Swiss Prot :

  Q99988

• Accession Number :

  Q99988

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  34 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  GDF15

• NCBI Official Name :

  Growth/differentiation factor 15

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Anand, I.S., et al. Circulation 122 (14) :1387-1395 (2010)

• Background Reference 02 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03 :

  Staff, A.C., et al. Gynecol. Oncol. 118 (3) :237-243 (2010)

• Background Reference 04 :

  Roth, P., et al. Clin. Cancer Res. 16 (15) :3851-3859 (2010)

• Other Product Names :

  Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  313104195

• Physical Properties :

  Liquid