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GDF11 Antibody

CAT: 0223-61-067Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-067Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
NCBI Gene ID
10220
Swiss Prot
O95390
Accession Number
O95390
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GDF11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
GDF11
NCBI Official Name
Growth/differentiation factor 11
NCBI Organism
Homo sapiens
Background Reference 01
Lee, S.J., et al., Curr. Opin. Genet. Dev. 9 (5) :604-607 (1999) .
Background Reference 02
McPherron, A.C., et al., Nat. Genet. 22 (3) :260-264 (1999) .
Background Reference 03
Gamer, L.W., et al., Dev. Biol. 208 (1) :222-232 (1999) .
Background Reference 04
Hillier, L.D., et al., Genome Res. 6 (9) :807-828 (1996) .
Other Product Names
Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11, GDF11, BMP11
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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