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NKAP Antibody

CAT: 0223-56-401Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-401Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
NCBI Gene ID
79576
Swiss Prot
Q8N5F7
Accession Number
Q8N5F7
Host
Rabbit
Reactivity
Human
Immunogen
This NKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human NKAP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NKAP
NCBI Official Name
NF-kappa-B-activating protein
NCBI Organism
Homo sapiens
Background Reference 01
D'Addabbo, A., et al. Artif Intell Med 46 (2) :131-138 (2009)
Background Reference 02
Pajerowski, A.G., et al. Immunity 30 (5) :696-707 (2009)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Chen, D., et al. Biochem. Biophys. Res. Commun. 310 (3) :720-724 (2003)
Other Product Names
NF-kappa-B-activating protein, NKAP
Tested Applications
WB
Protein ID
74728990
Physical Properties
Liquid

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