PRMT8 Antibody

• Background :

  Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.

• NCBI Gene ID :

  56341

• Swiss Prot :

  Q9NR22

• Accession Number :

  Q9NR22

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  45 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PRMT8

• NCBI Official Name :

  Protein arginine N-methyltransferase 8

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lee, J., J. Biol. Chem. 280 (38), 32890-32896 (2005)

• Other Product Names :

  Protein arginine N-methyltransferase 8, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, PRMT8, HRMT1L3, HRMT1L4

• Tested Applications :

  WB

• Protein ID :

  88983969

• Physical Properties :

  Liquid