PRMT5 Antibody

• Background:

  This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  10419

• Swiss Prot:

  O14744

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human PRMT5 (NP_006100.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 73kDa

• Fragment:

  IgG

• Symbol:

  PRMT5

• Positive Control 2:

  Jurkat

• Positive Control 3:

  Raji

• NCBI Official Name:

  Protein arginine methyltransferase 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PRMT5, JBP1, SKB1, IBP72, SKB1Hs, HRMT1L5

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid