STUB1 Antibody

• Background:

  STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al., 2008 [PubMed 18411298]) .

• NCBI Gene ID:

  10273

• Swiss Prot:

  Q9UNE7

• Accession Number:

  Q9UNE7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the C-terminal region of human STUB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  STUB1

• NCBI Official Name:

  E3 ubiquitin-protein ligase CHIP

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Stankiewicz, M., et al. FEBS J. 277 (16) :3353-3367 (2010)

• Background Reference 02:

  Naito, A.T., et al. Circ. Res. 106 (11) :1692-1702 (2010)

• Background Reference 03:

  Loffek, S., et al. Hum. Mutat. 31 (4) :466-476 (2010)

• Background Reference 04:

  Graf, C., et al. Biochemistry 49 (10) :2121-2129 (2010)

• Other Product Names:

  HGNC:11427

• Tested Applications:

  WB, Flow

• Protein ID:

  78099173

• Physical Properties:

  Liquid