TXNL2 Antibody

• Background:

  GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity) . May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

• NCBI Gene ID:

  10539

• Swiss Prot:

  O76003

• Accession Number:

  O76003

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This TXNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TXNL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GLRX3

• NCBI Official Name:

  Glutaredoxin-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ohayon, A., et al. J. Histochem. Cytochem. 58 (9) :799-806 (2010)

• Background Reference 02:

  Haunhorst, P., et al. Biochem. Biophys. Res. Commun. 394 (2) :372-376 (2010)

• Background Reference 03:

  Ohayon, A., et al.Immunotoxicol 7 (1) :8-14 (2010)

• Background Reference 04:

  Cha, M.K., et al. Cancer Epidemiol 33 (3-4), 281-287 (2009) :

• Other Product Names:

  Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PICOT, PKC-theta-interacting protein, PKCq-interacting protein, Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2

• Tested Applications:

  WB, Flow

• Physical Properties:

  Liquid