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TXNL2 Antibody / GLRX3

CAT: 0800-R32534Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32534Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glutaredoxin-3, also called Thioredoxin-like protein 2 or TXNL2, is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O76003
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids L89-S177 from the human protein were used as the immunogen for the TXNL2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the TXNL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TXNL2 antibody is available for research use only.
Storage Conditions
After reconstitution, the TXNL2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Differences in protocols and secondary/substrate sensitivity may require the TXNL2 antibody to be titrated for optimal performance.
Image Legend
Western blot testing of 1) rat testis and 2) mouse testis lysate with TXNL2 antibody at 0.5ug/ml. Expected molecular weight: ~40 kDa.
Product Datasheet
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