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XCR1 Antibody

CAT: 0223-56-196Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-196Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
2829
Swiss Prot
P46094
Accession Number
P46094
Host
Rabbit
Reactivity
Human
Immunogen
This XCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-333 amino acids from the C-terminal region of human XCR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
XCR1
NCBI Official Name
Chemokine XC receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397 (4) :756-761 (2010)
Background Reference 02
Crozat, K., et al. J. Exp. Med. 207 (6) :1283-1292 (2010)
Background Reference 03
Bachem, A., et al. J. Exp. Med. 207 (6) :1273-1281 (2010)
Background Reference 04
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Other Product Names
Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1, XCR1, CCXCR1, GPR5
Tested Applications
WB
Protein ID
1170008
Physical Properties
Liquid

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